Abacavir EP Impurity D HCl CAS 1443421-67-7 (free base)
| CAS No. | 1443421-67-7 (free base) |
| Molecular Formula | C14H18N6O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Abacavir EP Impurity D HCl (CAS 1443421-67-7 (free base), C14H18N6OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Abacavir EP Impurity D HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 322.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Abacavir EP Impurity D HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18N6O HCl |
| Molecular Weight | 322.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Abacavir Standards
- Abacavir Impurity 7 (CAS 120503-69-7)
- Abacavir-d4 (cyclopropyl-2,2,3,3-d4) (CAS 1217731-56-0)
- Abacavir Impurity 10 (CAS 1233918-37-0)
- Abacavir EP Impurity C (CAS 124752-25-6)
- Abacavir-d4 (CAS 1260619-56-4)
- Abacavir-D4 Hydrochloride (CAS 1346605-40-0)
- Abacavir 5’-Phosphate (CAS 136470-77-4)
- Abacavir (CAS 136470-78-5)
Recommended Standards
- Empagliflozin Impurity 3 (CAS 2452301-09-4)
- Brivaracetam Impurity 67 (CAS 357338-13-7)
- Vonoprazan Impurity 32 (CAS 2514742-82-4)
- 4,5-Dichloro-2-(2-chlorophenyl)thiazole (CAS 1355189-38-6)
- 2-Amino-2-(1,1-dioxo-1lambda6-thiolan-3-yl)acetic acid (CAS 1218504-97-2)
- (2-Isopropylthiophen-3-yl)boronic acid (CAS 2364586-73-0)
- 2-((1-Cyanocyclopentyl)amino)-2-oxoethyl 2-(1,3-dioxoisoindolin-2-yl)-4-(methylthio)butanoate (CAS 1014518-60-5)
- Pantoprazole Impurity 28 (CAS 97963-76-3)
- 1-(Isopropoxymethyl)cyclobutane-1-carboxylic acid (CAS 1387557-40-5)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com